Cook Medical Associates offers Functional and Evidence Based medicine in Ocala, FL — accepting insurance, memberships, and Direct Primary Care. Focused on Diet, Exercise, and Sleep. Led by Calvin Cook, MD, CCSH, the practice supports individuals seeking practical guidance for long-term wellness.
Cook Medical Associates is led by two physicians who specialize in Internal Medicine, dedicated to combining the best of functional and evidence-based medicine. We take the time to understand your whole health picture — not just your symptoms. Located at 3301 SW 34th Circle, Suite 302, Ocala, FL 34474 — behind the Paddock Mall.
Internal Medicine · Ocala Native
Dr. Calvin Cook is an Internal Medicine physician and Ocala native who brings together clinical medicine, military service, and sleep medicine expertise. A decorated veteran who served as a Hospital Corpsman with the Fleet Marine Force, he holds an MBA in Health Care Management and specialized credentials in sleep medicine (RPSGT, CCSH). His clinical interests include internal medicine, sleep optimization, metabolic health, weight management, cardiovascular risk reduction, and lifestyle-focused preventive care.
Internal Medicine · Osteopathic Medicine
Dr. Jonathan Grube is an Internal Medicine physician with a BS in Biochemistry from Oklahoma City University and a DO from Lincoln Memorial University–DeBusk College of Osteopathic Medicine. He completed his residency at UCF/HCA Ocala Regional Medical Center, where he received the HCA Healthcare Hero Award. An active medical researcher with peer-reviewed publications, he holds ACLS and BLS certifications. His osteopathic approach focuses on treating the whole person through preventive care, education, and evidence-based medicine.
| Direct Primary Care — New Patient / Follow Up | $175 / $120 |
| CPAP Management | $120 |
| Membership for Chronic / Acute illness / CPAP < 60 years $100, > 65 years | $120 |
| Basic Hydration Drip | $90 1 liter of fluids |
| Immune Boost Infusion | $135 |
| Energy & Recovery Drip | $150 |
| NAD+ Infusion | $150 |
| GLP-1 Initial Consultation | New Patient / Member Pricing |
| Semaglutide Program | Contact for pricing |
| Tirzepatide Program | Contact for pricing |
| Home Sleep Study | $150 / $175 for multi-night NightOwl |
| CPAP Setup & Management | Discounted Pricing for Members |
| Hormone Consultation | New Patient / Member Pricing |
| Testosterone Therapy | Discounted through compound pharmacy |
Patient Portal is a secure, convenient, and easy-to-use website that gives you round-the-clock access to your health information. View labs, medications, and immunization records. Get reminders. Exchange messages with your doctor. Stay informed and take charge of your health!
Need help logging in? Call us at 352-873-7510
Access your health record with the healow TM smartphone app. Along with the features you get with our Patient Portal, the healow app can manage multiple accounts (all family members), set medication and appointment reminders, and use trackers to help manage health. The healow app is a secure and convenient way to manage what’s important and puts YOU in control of your health.
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